Bioidentical hormone pellets, made from either estradiol or testosterone, are tiny—slightly larger than a grain of rice and smaller than a Tic Tac. These small, solid cylinders are designed to deliver hormones directly into the body.

The procedure to insert the pellets is quick and straightforward. A local anesthetic is applied, a small incision is made, and the pellets are placed under the skin in fatty tissue—typically in the upper buttocks or flank. The incision is then closed, and no stitches are needed.

Once in place, the pellets release hormones into the bloodstream in response to your body’s activity levels. For example, during physical exercise or times of emotional stress, the hormones are naturally released to help maintain balance and reduce symptoms like mood swings or energy dips.

Subcutaneous hormone pellets have been used since the 1930s to treat hormone imbalances. Research has consistently shown that this method is one of the most effective ways to deliver hormones for both men and women.